Wako Hyaluronic acid LT for automated measurement of Hyaluronic Acid
A unique new test for the automated measurement of Hyaluronic Acid (HA) in serum and plasma using standard biochemical analysers is now available. Patient samples are mixed with a recombinant HA binding protein (HABP) in the HA LT reagent. Latex particles coated by anti-HABP antibody are added resulting in increasing turbidity.
The high molecular weight glycosaminoglycan HA is the best single biomarker for hepatic fibrosis. It shows a negative predictive value (NPV) of up to 100% for cirrhosis of various aetiologies. Several biomarker combinations have been validated to enable the accurate staging of different fibrosis stages as non-invasive alternatives to liver biopsies. Fibrometer and Hepascore are the most powerful scores that include HA in their panels. HA LT by Wako can significantly improve such scores in terms of automation, simplicity and analytical performance. The test is highly precise, accurate and offers a high linear range from 10 to 1000 ng/mL.
Articles:
Guéchot J et al. Automated assay of hyaluronic acid in serum. Immuno-analyse et biologie spécialisée (2008) 23: 148-152
Dr. Robert Küper
Distributor for Russia: Vital Diagnostics SPb, Address: pr. Engelsa 27, build. 12B, 194156, Russia
